SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3988771422e39262cbf283d6f43ee5873b348684dba2d87d1da3d2da055ef004' 
  AND token = 'RCS+LRAXg2j8ga2ZxfXED32JjWD0LjBjxDZXmBGO0YY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}