SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '178b8f2193f4f4b8d5b80d60b49630d72b9124d6dbadd940e08f55524d3b2e09' 
  AND token = '1js9hzi/8frInjZ8HIOzuM0W8a6VRHFxBowbpgL33+A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}