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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a89006f335ba1e676181dfc752639ccd5b8f654f3e924d819ebfe8f3efe8cfd' 
  AND token = 'kVPTWH3OMYXRY+f8MdzR7Ko6U1y9yCIVOHm7pnlJrYw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}