SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c5d491b83f1dfc364e833cf33aebcd1d281654b42ddc4e17e19eb7fd5e2cb58' 
  AND token = 'xizjePymyAiLQRhiNdiDUQ0196GC1p0zXy2I0t+9u/Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}