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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43ab41ea8ba243b507c0f4930ad790d12a00fb7a02b2e90a519b83cd9dfbd191' 
  AND token = 'sbDp9RM+1dp0s8ASuK5PnT5g7aKxjOtKbrDgtPQ8Zb4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}