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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '483a78a65592f0e14bb58c9fb16ea52f3ec7ecba66fc67c818c3c4ec6c408544' 
  AND token = 'EbZTHDgnGyW5WvHXIakYRzvchkhk7ihBUwME4eWo8U8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}