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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46276bab19cec2c9e58eeff3809ed0b2264f3ec4d8f9e84fc1382eca6013142c' 
  AND token = 'EbK3+uE2yok0Mu/lbx3Z5A6yywcnnvoLo1PdivI99Nk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}