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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c7025de62def82650c49bd7d4e5bdf816b0f0b79714d781b96087b165fa6290' 
  AND token = 'FMCPhWRSuml4LLgDnNgx6JuOX7x+1Vkf7D2xMDqvCRE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}