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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b298d3c8f051347e4a6e394c622e544f864fd65d38d5a6a4acbed198144e5a0' 
  AND token = 'HsID19CLPWmXTim8/k91LtXQw9OqRxQWn+nGz5eaRRY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}