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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f49f9e73ed8513d33c6cd95b6138abc7b5a6606006c1959f1e76691d4f3b2f0f' 
  AND token = 'vG7xEX9e41zC+YYuiWGIVWk5lOIoE3scoBoaecbNGMc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}