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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ad2184ae0eb8701b0e6d90bd71dc5c7e14df6619a7c39e01bd83067953f8069' 
  AND token = 'B0s6UloMSlVsJsR1EOZE4/Ct0b2LzkdUP+0319bms64=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}