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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '146cb023538296f3bd186d293b6ac1916444829d7993a1757533262f0c693270' 
  AND token = 'EotwW2DnkJPSp44CzWzaxd2jpU+h+jNM6L2RudgWxBA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}