SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e95d475b9527b43c2d34268e7f3180a08eef69e89e8374641daa0c311ba43d88' 
  AND token = 'jlGMk2gOlUBe6r7WUlJ9BFS8TAoRn5Ls3JafimG4dF8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}