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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27f71c1c09e08d797d37399097953e57a99f9ac47fcdb676e584d18f4fc1b9d6' 
  AND token = 'NfhrFUMlz2V+bkL3HQ7R8gwdxnPlGQD2sWYiwNexScg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}