SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74c3db8e4ed6812af79148e12c688852190c86c2d590e017ccfe688fd1146f99' 
  AND token = '8twvtDqGVHiTLhznr+r/znkKYlMdMd0L+1PdKv6+dEE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}