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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa4110d0aed5bf156acbc69553bcdab165ffdd7259aaa96fa721eadb00011a0d' 
  AND token = 'ng0x1IoK8wlG+wPLSQAjhEq9ZPYbvPpO+tun5Po0eTw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}