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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '487124b621901d4db5611019977c1d11d46f743f380fc6d5b829986c8899de15' 
  AND token = 'cuEFJ3NHomx3LEYkqMgRj6FGUEBw/BibN8N1N2aIjqs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}