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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f5b3fbeedda309d60a80e4897309476395d325423e5053d40475c2a097f87c8' 
  AND token = '5SVg/5ympI8kP8QmewaHB3ZXdJF5XiyKPUXfVJ19e4w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}