SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cf44b36459b92a48d018139d62c9727108f3cf326650759bdeba660465309df' 
  AND token = 'qd0KtXFT+wPXTo+qa37CZX6e1oGz+iE63lyzoy2Tbwg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}