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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '606e6e3f1d7f5dc2df0c2ff22b7279f3161bf7f75cb95335291343f1e0147439' 
  AND token = 'f5CziJT3vA6nycsxG/TR5e5mt65pHf2y2UR36fKtoiw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}