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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4d2cd88c8c19d18cfd65d6b1696f4e9dccaba5acd27b1d1b3c4aa149a09549c' 
  AND token = 'zj3d1yhTkIvpVGWfvSUmCpuWG1JtCZVE1AZojXSRM5Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}