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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04cb01bf00df2abb3c743e236ed053b12c4cb74c41224e9c8d85eb3ffff71c2a' 
  AND token = 'gVsQjK48gQ8PUqLXmjQB/lnkSxI2keK314BnanfyNeM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}