SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e45d6537c23e3a8d85a2ba86d531d8dbbf73377ed13ad3e57ce5d4ec239b366' 
  AND token = 'k3bJNG37xSxpxCHe4cnCkkFsKQhNknWwFmp7CRvFqeo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}