SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16571712acd1941e92de327530103cb2628e77813bd32c91e2536a047d8a7df2' 
  AND token = 'UDMj5PbYvuS6GNrj+aaAbXQJIfkbQpoMGh+yQFIMzaA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}