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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f57e1e9701baa92da753c78d6bd32af931ff6d6de83401f59b7d4335eb71d40' 
  AND token = 'HjR5+yRpiikC3097EYW6/oKnDSmd7XvQUEc2uW6CgBw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}