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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25bc53963f07a273d428077bba64aa929c9c1b5616465c05fe298480e24207b4' 
  AND token = 'v0530+a1sJd2BILo+na0eXA7D53zRiDbiVCHkID5Zfc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}