SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '924b2e3d705ab017bf3fe84f219bd5b5385f510f293429b040487996173b239e' 
  AND token = 'fmxrgZ8ck2tTHfa243rt3q7ZOolHRWoqszbAlQGDGYQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}