SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b1018ddce96ef2b0870932003e3a75ae310f3536d27e564c390d723af362334' 
  AND token = 'eu9M2u+ouglr705vlMmfmAYlbO85glhm+obZ8npgyNU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}