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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2914d661079efaf1178c232fbcfe78ca2ee26751664c15d4336e9add41f66c61' 
  AND token = 'BuGdo9OnrB7t8NBTxCxdXOIpO/dS2WFOP5xaOu39Y6w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}