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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '193a3c984a1bd1985364a65e1afc2eb9171b3d3d900330657ba151c308b2b05c' 
  AND token = 'RI4fuYX9h2hWHKZXrCGBM3bcY4x2rCaIlEBGDDHTHqk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}