SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cfddd7d1cda75dff2dfaf7a243e5677b6353283a0bd248aa5a8320d84c3e4384' 
  AND token = 'UeWkzG/nzQOhGFlT6vwBPLmFeuRISHZW6x7TWu6qKFc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}