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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc1ea940a95b9f29a32f40e11d5680d9fb03bee2f24b714fab269c579ef9bcba' 
  AND token = 'kQ2rI+lp/GlidPV9Zj+4XIiGY/r+WALR9CrK957xmCg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}