SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46b736c9d2c331ff2119cadb564064fbcfed27e07e2b2b44fa99787c06eba148' 
  AND token = 'NnLvn9xLecFgsO/HU6b0iH8kIFqpVKTgXZ98xtqKdbk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}