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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6afb2bfc748d6dcf19aca036b50bfd9f75facb7879275cf11c7dab89009a2dc1' 
  AND token = 'Maq0FR4SzNnMzd9JmxxTAfxyBrJaw1giBx7+M4W25hk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}