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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d6f4d016f7c7c1b10a8c081086f0c3712edcfaf95679a53b897b44f531fa2bf' 
  AND token = 'W2b+w4OrvvYbXMwBRcWecWysIjCvPSF86a/CrUeGXBc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}