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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da13219eb2d3ffa1fd86181feef0aa022f4e676ba678d7031d2d2aa5a89f1e27' 
  AND token = 'eIYTuqqE9ckDzMF2nd2vQmxsXpHZCde8IPTjszl+7sI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}