SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c09c0dd6dd82a4bd69f8935deb61b49d670124e0eedb2a089f0c257e76ed5806' 
  AND token = 'IGvtOaAumwvL20JvgU1kmbNU6uipsbPb58RAHyT4iWI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}