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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28e31037a611c1a9c5cd43aa909d33b143b78055fa5c679041d9e89aa1b5c860' 
  AND token = 'gfvTSRDpg/FJf/OCoD+aiPBAO9MzVWXroNZnOue6Vy0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}