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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ef8554ec772ef65fcf9e921f9908d1b20a0dd3e793ba616f31be6998cfd8a23' 
  AND token = 'oYy/SGt2ZnFYw34BtHQYmwYxER2tCWiudjZ3lGM2SQ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}