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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49ec242aba8164878620c6f8ee2d5fa37ceccaed7ad577959c9ae97be04a6240' 
  AND token = 'AKPbpUPSL0GyZ2nO4DcH/e4CETg5kVcCjtI8dKewgGQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}