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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7326cb78ae0ed6dee8608b4b81b6142349a018a8cbc8c62b9b50e0116c8e1c46' 
  AND token = 'wvHWE0+lXDhU83ooqHSuMRGVOpt9PIZZLqfU5b+C14I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00060

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}