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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df3a9b56ca89dfd21c0b471acf00152ea779f1ad0f64c398056498e007f945b3' 
  AND token = '1kt97SFMFy+VleLV6heJroIBH0eS7mDLlaUYskU3Aso=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}