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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17182160a373ef66fd27feb6a294dc902911bf3b78441a24f855b623a5baced7' 
  AND token = 'zXNDxpAwE/R36HDxnrim4mbIilLtjFf+KBiCh1eDx2U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}