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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0cee092bb9e2666b139d64a9a994b5f63d4285fca94a7297cb7e488b539a9904' 
  AND token = 'rWQWhlrCO1QKds3thacgye6FK3qBUB5toiVPM9saqEw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}