SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1a6e0b86abf499abb8d5fe12f0591b755ddce6b653e56c3e3b2133443ba0e50' 
  AND token = 'oUZff3iZekOGjLyn00hyfPP65djO2m+p4GsDkQ9MO7M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}