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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c59cca58056e70906fcea329160ddc14bc9a0280bf30c781d0e7272bddb2582' 
  AND token = '8KxreMn6ubGulaLP2hctOp+7kke6+OTsUE1r3AMtDr8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}