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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2925caed6050fc6e330991d2106243991684d6e75bc9ec5f34c64ab361effbeb' 
  AND token = 'tr5HH2yL8LZ+MG4qNVVi5dcdH5d5Pkw19kvU++ixhnQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}