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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f31b9c70cd83ef40f536b7d68d7690a3f913a106755e040e5ec2565e9889f27e' 
  AND token = 'Zt+9tHL+NUPDu/xU0D58rwtGj7w/DHqdjQodzX60w9c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}