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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efc0cc96a4fdad88b76c6a06ee83f6e08739a004e61e2dd26f0136cd5a286f9b' 
  AND token = 'q2LxHbo/gALlAYFdHT8Sb31E218Yk5CBNbFNKTQUNGs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}