SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7dd4ec78542a54d99a33c62b64ab1e2fa97f8f7dcf52816692cb461e3b0edf1b' 
  AND token = 'YyLqhHnTfeftGvFAaEUXxSazYNp36IY031lkSpiTxfk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}